The ESSIC obtained consensus on a new classification of IC and proposes to replace the name interstitial cystitis (IC) by bladder pain syndrome (BPS) followed by a type indication. In a transition period the name bladder pain syndrome/interstitial cystitis (BPS/IC) could be used parallel with BPS. Click here for more details.
Assessing urgency in interstitial cystitis/painful bladder syndrome.
Diggs C, Meyer WA, Langenberg P, et al. Urology 2007;69:210-4 • the O'Leary-Sant Symptom Index appeared to underreport urgency
• asking about urgency "with little or no warning" underestimated the prevalence and degree of urinary urgency
• the authors conclude with the question that may have pathophysiological importance: "why do patients with IC/PBS have urgency ?"
The molecular basis of urgency: Regional difference of vanilloid receptor expression in the human urinary bladder. Liu L, Mansfield KJ, Kristiana I, et al. Neurourol Urodyn 2006 Oct 2; [Epub ahead of print]
• the authors conclude that symptoms of sensory urgency were associated with the increased expression of targeting vanilloid receptor TRPV1 mRNA in the trigonal mucosa; no upregulation or regional differences of TRPV1 mRNA were seen in idiopathic detrusor overactivity patients
• TRPV1 may play a role in SU and premature first bladder sensation on filling
